History of creation
Antidepressants are the preparations facilitating or preventing depression. Substances possessing exciting effect were actively applied for treatment of depressions, capable to cause an euphoria condition (opium and other opiates, caffeine, a ginseng) before antidepressants' opening. To reduce alarm and excitability, for example, bromine salts were applied. But the foundation of antidepressants became the present revolution in psychopharmacology in early fifties. Since then, already throughout half a century, these preparations are the basic agent for struggle against depression. In spite of the fact that the era of antidepressants has begun recently, it already has its "creation myths".
From the beginning of the twentieth century researchers studied various substances, trying to synthesize a preparation facilitating symptoms of depression, but all experiments ended with failure. The first antidepressant has been opened in 1957 absolutely casually when doctors have paid attention to action of a preparation called Iproniazidum which was applied at complex treatment of tuberculosis. Except its main effect, it has been also noted a collateral effect which showed unusual rising of mood among sick people. Soon this preparation was begun to use for simplification of depression symptoms as it was not worthy as an agent from tuberculosis.
